Costello, et al. Systematic intervention to reduce central line-associated blood-stream infections rates in a pediatric cardiac intensive care unit. Pediatrics 2008; 121:915-923

This study reports of a systematic intervention to reduce central line associated bloodstream infections in a pediatric cardiac intensive care unit. The addition of the MaxPlus Clear™ Positive Displacement Connector lead to a break in the plateau resulting in a BSI rate of 2.3 per 1000 catheter days, a 51% decrease.

• “For access to CVLs. We converted our needleless connector system from a luer lock       activated valve system to a device that has a flat access surface and contains a positive      displacement valve (MaxPlus needleless connector).”
• “We estimated an annual attributable cost savings of $236,000 to $782,000.”